Research & Developments

1. Research Grants

Project Title
Investigators
Funding Agency
Development and commercialization of fluorescence-based Rapid COVID-19 Detection Kit (June 2020)
Dr. Rakesh Bijarnia
TDB-Govt. of India, Rs. 47 Lakhs/-

2. INVITED LECTURES

  1. Immunodiagnostics & its importance in entrepreneurship. 15 February, 2020, 2nd International Conference, Society for research development in health Sciences, Dadasaheb Balpande College of Pharmacy, Nagpur
  2. Immunodiagnostics & its prospects in entrepreneurship. 28 March, 2019, Department of Biotechnology, Chitkara University, Chandigarh
  3. Insights of vascular calcification pertaining to its treatment and mechanism. 11 August, 2014, Department of Biochemistry, Panjab University Chandigarh, India
  4. A journey: Nanobacteria to nanoparticles. 20 December, 2013, Institute of Nanoscience and Technology, Mohali, Punjab, India

3. RESEARCH Publications

  1. Tanvi Sharma, Rakesh Kumar Bijarnia, Tanzeer Kaur (2022). Development of Lateral Flow Assay for the Detection of Tamm Horsfall Protein in Urine. Letters in Applied NanoBioscience. DOI: 10.33263/LIANBS121.016
  2. Kaur N, Singh R, Dar Z, Bijarnia RK, Dhingra N, Kaur T. (2020). Genetic comparison among various coronavirus strains for the identification of potential vaccine targets of SARS-CoV2. Infect Genet Evol. 2020 Jul 31;104490. DOI: 10.1016/j.meegid.2020.104490 .
  3. Sharma S, Parmar A, Bhardwaj R, Bijarnia RK, Kaur T. (2018). Design and Characterization of Apocynin Loaded PLGA Nanoparticles and their In vivo Efficacy in Hyperoxaluric Rats. Curr Drug Deliv. 2018;15(7):1020-1027. doi: 10.2174/1567201815666180228163519.
  4. Bhardwaj R, Bhardwaj A, Tandon C, Dhawan DK, Bijarnia RK, Kaur T. (2017). Implication of hyperoxaluria on osteopontin and ER stress mediated apoptosis in renal tissue of rats (2017). Exp Mol Pathol. Jun;102(3):384-390. doi: 10.1016/j.yexmp.2017.04.002.
  5. Aghagolzadeh P, Bachtler M, Bijarnia R, Jackson C, Smith ER, Odermatt A, Radpour R, Pasch A (2016). Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-α. Atherosclerosis. 251:404-414.
  6. Rakesh K Bijarnia, Matthias Bachtler, Prakash G Chandak, Harry Van Goor, Andreas Pasch (2015). Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats. PLoS One, 10(4): e0124881.
  7. Deepika Aggarwal, Rajeev Kaushal, Tanzeer Kaur, Rakesh Bijarnia, Surinder Singla (2014). The most potent antilithiatic agent ameliorating renal dysfunction and oxidative stress from Bergenia ligulata rhizome. Journal of Ethanopharmacology, 158: 85-93.
  8. S. Nayak, Tanzeer Kaur, S. Mohanty, G. Ghosh, R. Bijarnia/R Chaudhary, L. Acharya, E. Subudhi. (2011) “In vitro and ex vitro evaluation of long-term micropropagated turmeric as analyzed through cytophotometry, phytoconstituents, biochemical and molecular markers”. Plant Growth Regulation, 64:91–98.
  9. R.K. Bijarnia, T. Kaur, S.K. Singla, C. Tandon. (2009) “A novel calcium oxalate crystal growth inhibitory protein from the seeds of Dolichos biflorus”. The Protein Journal, 28: 161-168.
  10. R.K. Bijarnia, T. Kaur, S.K. Singla, C. Tandon. (2009) “Oxalate mediated oxidant- antioxidant imbalance in erythrocytes; role of N-acetyl cysteine. Human and Experimental Toxicology, 28(4): 245-251.
  11. T. Kaur, R.K. Bijarnia, B. Nehru. (2009) “Effect of concurrent chronic exposure of fluoride and aluminium on rat brain”. Drug and Chemical Toxicology, 32: 215-221.
  12. T. Kaur, R.K. Bijarnia, S.K. Singla, C. Tandon. (2009) “Purification and characterization of an Anticalcifying protein from the seeds of Trachyspermum ammi (L.)”. Protein and Peptide Letters, 16 (2): 173-181.
  13. T. Kaur, R.K. Bijarnia, S.K. Singla, C. Tandon. (2009) “In-vivo efficacy of Trachyspermum ammi anticalcifying protein in urolithiatic rat model”. Journal of Ethanopharmacology, 126(3): 459-462
  14. R.K. Bijarnia, T. Kaur, K. Aggarwal, S.K. Singla, C. Tandon (2008) “Modulatory effects of N-acetylcysteine on hyperoxaluric manifestations in rat kidney”. Food and Chemical Toxicology, 46: 2274-2278
  15. R.K. Bijarnia, T. Kaur, P. K. Naik, S.K. Singla, C. Tandon (2008). “In-silico study on interaction of active binding sites of proteins with calcium oxalate monohydrate”. Online Journal of Bioinformatics, 9 (2): 92-107.
  16. R.K. Bijarnia, T. Kaur, S.K. Singla, C. Tandon. (2007) “Reversal of hyperoxaluria induced alteration in rat liver by administration of N-acetylcysteine”. Drug and Chemical Toxicology, 30:229-240.
  17. R.K. Bijarnia. (2014) “The prospective applications and challenges of Calcium Phosphate Nanoparticles”. Innovations in Pharmaceuticals and Pharmacotherapy, 2(4):403-408.
  18. R.K. Bijarnia, T.Kaur, S.K. Singla, C.Tandon (2010) “Non surgical management therapies for Kidney stones”. Journal of Pharmaceutical Education and Research, 1:21-25.
  19. C. Tandon, R.K. Bijarnia, S.K. Singla, (2006) “Molecular aspects of Urolithiasis”; Panjab University Research Journal. 56:1-12.

4. CONFERENCES/ABSTRACTS

  1. Parisa Aghagolzadeh, Matthias Bachtler, Rakesh K. Bijarnia, Andreas Pasch (2014). Calciprotein Particles Induce Calcification of Vascular Smooth Muscle Cells in vitro. American Society of Nephrology (ASN), Kidney Week Nov 11-16, Philadelphia, PA, USA
  2. Rakesh K. Bijarnia, Monique Niklaus, Prakash G. Chandak, Parisa Aghagolzadeh, Andreas Pasch (2014). Amelioration of vascular calcification by sodium thiosulfate: role of matrix vesicles. Organized by International Bone and Mineral Society at Sun Valley, Idaho, USA. Abstract published in journal IBMS BoneKEy.
  3. Parisa Aghagolzadeh, Matthias Bachtler, Rakesh K. Bijarnia, Andreas Pasch (2014). Sodium Thiosulfate by Conversion to H2S Could Prevent Calciprotein Particle-Induced Vascular Calcification. Annual Conference, University of Bern. Switzerland
  4. Rakesh K. Bijarnia, Monique Niklaus, Prakash G. Chandak, Andreas Pasch (2013). Sodium thiosulfate prevents the vascular calcifcation in uremic rats. 45th Swiss Society of Nephrology, Interlaken, Switzerland. Abstract published in European Journal of medical sciences:Swiss Medical Weekly magazine
  5. Rakesh K. Bijarnia, Andreas Pasch (2013). Sodium thiosulfate ameliorates oxidative stress and preserves renal function in ethylene glycol-treated rats. 50th ERA-EDTA congress, Istanbul, Turkey. Abstract published in Nephrology Dialysis and Transplantation (NDT) proceedings, 28, i388
  6. Prakash G. Chandak, Rakesh K. Bijarnia and Andreas Pasch (2013). Calciprotein particles induce an inflammatory response in macrophages. 45th Swiss Society of Nephrology, Interlaken, Switzerland. Abstract published in European Journal of medical sciences: Swiss Medical Weekly magazine
  7. Rakesh K. Bijarnia, Tanzeer Kaur, S. K. Singla and C. Tandon. (2009). “A novel antilithiatic protein from the seeds of Dolichos biflorus”. Role of Biotechnology in society. Conference Conducted by: Punjab Science Congress, Punjab Agriculture University, Ludhiana.
  8. Rakesh K. Bijarnia, Tanzeer Kaur, S. K. Singla and C. Tandon. (2009). “A novel antilithiatic protein from the seeds of Dolichos biflorus”. Role of Biotechnology in society. Conference Conducted by: Punjab Science Congress, Punjab Agriculture University, Ludhiana.
  9. S. K. Singla, Rakesh K. Bijarnia, Tanzeer Kaur, Chanderdeep Tandon (2008). “Similarity of a calcium oxalate crystal growth inhibitor protein from seeds of Dolichos biflorus with calnexin of Pisum sativum”. National conference on Genomics, Proteomics and System Biology, Bangalore
  10. Priyadarshini, Rakesh K. Bijarnia, Tanzeer Kaur, S. K. Singh, Chanderdeep Tandon. Comparison of the inhibitory activity of isolated lipids and proteins from calcium oxalate stones.(2008) Abstract published in Indian Journal of Urology 24: Supplement 2: S111 at 9th Asian Congress of Urology, New Delhi Oct 2-5, 2008.
  11. Tanzeer Kaur, Rakesh K. Bijarnia, P. K. Naik, S. K. Singla and C. Tandon. (2007). “Molecular interactions of calcium oxalate with protein inhibitors of crystallization: A combined approach of docking and MM-GB/SA.” Biophysics in Medicine & Biology. Conference Conducted by: Indian biophysical society at Panjab University Chandigarh.
  12. Rakesh K. Bijarnia, Tanzeer Kaur, S. K. Singla and C. Tandon. (2006) “Comparative analysis of the anti-calcifying properties of different plants”. Emerging Trends in Biochemistry (Symposium), Panjab University Chandigarh